Condensin is a motor
Condensin plays crucial roles in chromosome organization and compaction, but the mechanistic basis for its functions remains obscure. I...
Helicases on crowded DNA
In physiological settings, all nucleic acids motor proteins must travel along substrates that are crowded with other proteins. However,...
Simulation of p53 on nucleosomes
The length of human genomic DNA is ~2m. The DNA is packaged into nucleus with diameter of ~10 μm. Even though it is highly condensed, the...